Abstract
Introduction:: Traumatic intracerebral contusion is a frequent factor culminating in death and disability, and its progression relates to unfavorable outcome. We evaluated the radiological factors associated with hemorrhagic progression of contusions (HPC). Materials and Methods:: Two hundred and forty-six patients were enrolled in this prospective cohort over a period of 1 year. Contusion volume was quantified using the ABC/2 technique, whereas progression was considered as >30% increase in the initial volume. Univariate and multivariate statistics were used to examine the correlation between the risk factors of interest and HPC. Results:: HPC was seen in 110 (44.7%) patients. Binary logistic regression showed in the final adjusted model that multiplicity (relative risk [RR]: 2.24, 95% confidence limit [CL]: 1.005.48), bilateral lesions (RR: 2.99, 95% CL: 1.088.25), initial volume of contusion (RR: 4.96, 95% CL: 1.8713.13), frontal location (RR: 1.42, 95% CL: 1.083.56), and presence of concomitant intracranial hematoma (extradural-RR: 3.90, 95% CL: 1.5110.01, subdural-RR: 2.91, 95% CL: 1.266.69, and subarachnoid-RR: 2.27, 95% CL: 1.015.80) were significantly associated with HPC. The overall mortality was 18.7% and was almost equal among patients with and without HPC. Mortality was significantly associated with Glasgow Coma Scale on admission (adjusted RR: 12.386, 95% CL: 4.78932.035) and presence of comorbid conditions (adjusted RR: 0.313, 95% CL: 0.1140.860). Conclusion:: Initial computed tomography scan is a good predictor of high-risk group for HPC.
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This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
