Abstract

Diffusion-weighted imaging: As the first diagnostic clue to Creutzfeldt Jacob disease.

Kumaran, Sunitha P Gupta, Kanchan Pushpa, BT Viswamitra, Sanjaya Joshy, EV

Abstract


We describe a case report where the diagnosis of sporadic Creutzfeldt-Jakob disease(CJD) was suspected by the magnetic resonance imaging (MRI) radiologist in a 75-year-old lady who presented with rapid cognitive decline. MRI revealed cortical T2 and FLAIR(fluid attenuation and inversion recovery) hyperintensities in bilateral fronto-parietal and temporo-occipital locations and showed significant restriction on diffusion-weighted images(DWI). In this case report, we discuss the role of MRI to suspect the diagnosis of CJD in appropriate clinical settings.


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