Abstract

Tuberculum sellae meningiomas: A series of 41 cases; surgical and ophthalmological outcomes with proposal of a new prognostic scoring system.

Palani, Arun Panigrahi, Manas K Purohit, Anirudh K

Abstract


Context:: Tuberculum sellae meningiomas have proved difficult to treat, partly because of their intimate association with the optic nerves and chiasma, hypothalamus, and internal carotid arteries. Aims:: The aim of this study is to analyze the degree of influence of various prognostic factors affecting visual outcome; the pattern of visual recovery and develop a scoring system for prognostication. Settings and Design:: This is a retrospective study carried out from January 2004 till June 2011. Materials and Methods:: Patients were analyzed on the basis of clinical, radiological, and surgical factors that appeared to affect the outcome. A special scoring system (according to the guidelines of the German Ophthalmological Society) was adopted to quantify the extent of ophthalmological disturbances. Statistical Analysis Used:: Comparison of categorical variables between the two was performed using chi-square test and a P value of 0.05 was considered significant. Logistic regression was used when multivariate analysis was required. Results:: Vision improved in 27% and deteriorated in 7.3%. A prognostic scoring system (score 413) was developed depending on the degree of influence of significant prognostic factors. The patients with a score of 6 had improved vision postoperatively (44%), whereas none of those with a score > 6 improved. Completeness of visual recovery was perceived in 100% of patients within 3 months. Complete resectability was achieved in 73% of patients. Conclusions:: The proposed scoring system is very useful in prognosticating the visual outcome of these patients. The patients with a score of 6 have the best visual outcome postoperatively. Complete resectability is better achieved with extended bifrontal and unilateral frontal approaches. Short-term postoperative visual outcome is a strong indicator of permanent visual outcome after surgery.


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